The Jackson Laboratory was founded in Bar Harbor, Maine in 1929 by former University of Maine and University of Michigan president C. C. Little under the name Roscoe B. Jackson Memorial Laboratory. The Jackson Laboratory is an independent, nonprofit biomedical research institution, dedicated to contributing to a future of better health care based on the unique genetic makeup of each individual. With more than 1,400 employees in Bar Harbor, Maine, and Sacramento, California, the Laboratory's mission is to discover the genetic basis for preventing, treating and curing human diseases, and to enable research and education for the global biomedical community. The institution is a National Cancer Institute-designated Cancer Center and has NIH centers of excellence in aging and systems genetics. The Laboratory is also the world's source for more than 5,000 strains of genetically defined mice, is home of the mouse genome database and is an international hub for scientific courses, conferences, training and education.