News tagged with morphogen


A morphogen is a substance governing the pattern of tissue development, and the positions of the various specialized cell types within a tissue. It spreads from a localized source and forms a concentration gradient across a developing tissue[citation needed].

In developmental biology a morphogen is rigorously used to mean a signaling molecule that acts directly on cells (not through serial induction) to produce specific cellular responses dependent on morphogen concentration[citation needed].

Well-known morphogens include: Decapentaplegic / Transforming growth factor beta, Hedgehog / Sonic Hedgehog, Wingless / Wnt, Epidermal growth factor, Fibroblast growth factor, and Retinoic acid[citation needed].

Morphogens are defined conceptually, not chemically[citation needed], so simple compounds such as retinoic acid (the active metabolite of retinol or vitamin A) may also act as morphogens[citation needed].

This text uses material from Wikipedia, licensed under CC BY-SA

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